AREDS2 formula

AREDS2 Supplement Formula

Also known as: PreserVision AREDS 2, AREDS formula

Vision

TL;DR

Specific combination of vitamin C (500mg), vitamin E (400 IU), lutein (10mg), zeaxanthin (2mg), zinc (80mg), and copper (2mg) validated by the NIH-funded AREDS2 trial for slowing AMD progression.
Safety: Well-studied. Individual component side effects apply. High-dose zinc may cause GI issues. Overall well-tolerated in the AREDS2 trial.
Cost: approximately $20-30/month.
Best for: Macular degeneration

What the research says

Macular degenerationHigh

Evidence

5/5

Onset speed

1/5

Typical dose: Per AREDS2 formula dosing

The gold standard. Large NIH-funded RCT showed 25% reduced risk of advanced AMD progression. Recommended by ophthalmologists worldwide. The single most evidence-backed supplement for any eye condition.

AREDS2 formula on Amazon

$20-30/mo (estimated)

See on Amazon →

*Link is just for your convenience - we do not make any fees

Safety & practical info

Safety:Well-studied

Individual component side effects apply. High-dose zinc may cause GI issues. Overall well-tolerated in the AREDS2 trial.

Interactions:Blood thinners, antibiotics

High-dose zinc interactions. Vitamin E anticoagulant effects. Separate from antibiotics.

Cost:$20-30/mo

PreserVision is the brand-name. Generic equivalents available.

Sources for this page include published meta-analyses, systematic reviews, and NIH dietary supplement fact sheets. All claims reflect the evidence as of early 2026.

This is not medical advice. Consult your healthcare provider before starting any supplement, especially if you take medications.

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