Beetroot

Beetroot Extract / Nitrate
Also known as: Beet juice, Dietary nitrate, Beetroot powder
Food-Derived

Content by: OpenSupplement Editorial Team  |  Medical review: pending  |  Last updated: April 13, 2026

Supplement Score
Beetroot500 mL juice or 6-12 mmol nitrate/day | $12-20/mo
Safety4
Interactions3
Cost4
Evid.Onset
Heart disease
44
Metabolic syndrome
33
4 PubMed references cited
4–5 Strong2–3 Emerging1 Weak|Methodology

TL;DR

  • Natural source of dietary nitrates that boost Nitric Oxide (NO)

  • High evidence for lowering blood pressure

  • Moderate evidence for improving athletic endurance and brain blood flow

  • Acts as a powerful vasodilator (opens blood vessels)

  • Excellent safety; turns urine pink/red (Beeturia)

  • Affordable: ~$12-20/month

  • Best for: High blood pressure, workout performance

What it is

Beetroot works through the 'Nitrate-Nitrite-Nitric Oxide' pathway. Nitric Oxide tells your blood vessels to relax and widen. This lowers the pressure on your heart and allows more oxygen-rich blood to reach your muscles and brain.

What the research says

Relevance: High
Typical dose: 500 mL juice or 6-12 mmol nitrate/day

Beetroot is a 'blood pressure buster.' Evidence. A meta-analysis of 16 trials found that beetroot juice significantly lowered systolic blood pressure by 4-10 mmHg within hours of consumption. Regular use helps maintain this effect, acting like a natural ACE inhibitor. [1][2][3][4]

Relevance: Moderate
Typical dose: Same dosing

Blood pressure and vascular benefits are particularly relevant for metabolic syndrome, where endothelial dysfunction is common [ref2]. Some studies suggest improved insulin sensitivity, though this evidence is less robust than cardiovascular effects. The nitric oxide pathway improvements may help with multiple components of metabolic syndrome including blood pressure and vascular health.

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Beetroot on Amazon

$12-20/mo (estimated)
See on Amazon

Safety

Extremely safe. Note: Don't panic if your urine turns pink (Beeturia); it is completely harmless. People prone to calcium-oxalate kidney stones should be careful with high doses, as beets are high in oxalates.

Interactions

  • PDE5 Inhibitors: May have an additive effect with drugs like Viagra or Cialis, lowering blood pressure too much.

Dosing

Standard Dose: 500 mg to 1,000 mg of extract, or 1 shot of concentrated juice. Timing: 2-3 hours before exercise or anytime for blood pressure.

Cost

Affordable. $12-20 per month.

The bottom line

Beetroot is the best 'whole-food' way to lower your blood pressure. It's a foundational supplement for cardiovascular health.

References

  1. Meta-analysisHeart diseaseMetabolic syndromePubMed
  2. ReviewHeart diseaseMetabolic syndromePubMed
  3. RCTHeart diseasePubMed
  4. Meta-analysisHeart diseaseMetabolic syndromePubMed

Sources for this page include published meta-analyses, systematic reviews, and NIH dietary supplement fact sheets. All claims reflect the evidence as of early 2026.

This is not medical advice. Consult your healthcare provider before starting any supplement, especially if you take medications.