Olive polyphenols

Olive Leaf / Olive Oil Polyphenols

Also known as: Olive leaf extract, Oleuropein, Hydroxytyrosol

HeartMetabolic syndrome

TL;DR

Polyphenols from olive leaves and extra virgin olive oil. Oleuropein and hydroxytyrosol are key active compounds. Part of the Mediterranean diet's cardioprotective mechanism.
Safety: Excellent. Very well-tolerated. Long dietary history. No significant adverse effects.
Cost: approximately $12-20/month.
Best for: Heart disease, Metabolic syndrome

What the research says

Heart diseaseModerate

Evidence

3.5/5

Onset speed

2/5

Typical dose: 500-1000 mg olive leaf extract/day

Multiple trials show blood pressure reduction and improved lipid profiles. Hydroxytyrosol has EU-approved health claim for LDL oxidation protection.

Metabolic syndromeModerate

Evidence

3/5

Onset speed

2/5

Typical dose: 500-1000 mg/day

Some evidence for improved insulin sensitivity and blood glucose. Anti-inflammatory effects support metabolic health.

Olive polyphenols on Amazon

$12-20/mo (estimated)

See on Amazon →

*Link is just for your convenience - we do not make any fees

Safety & practical info

Safety:Excellent

Very well-tolerated. Long dietary history. No significant adverse effects.

Interactions:Blood pressure meds, diabetes meds

Additive blood pressure and glucose-lowering effects. Monitor if on antihypertensives or diabetes drugs.

Cost:$12-20/mo

Affordable. Standardized to oleuropein content.

Sources for this page include published meta-analyses, systematic reviews, and NIH dietary supplement fact sheets. All claims reflect the evidence as of early 2026.

This is not medical advice. Consult your healthcare provider before starting any supplement, especially if you take medications.

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