Valerian
Content by: OpenSupplement Editorial Team | Medical review: pending | Last updated: April 13, 2026
TL;DR
Traditional herbal sedative used since ancient Greek and Roman times
Strongest evidence for improving sleep quality and reducing sleep latency
Acts as a mild GABA-ergic agent, similar to a very weak benzodiazepine
Generally safe but can cause 'valerian dreams' or grogginess in some
Affordable: ~$5-12/month
Best for: Chronic insomnia, sleep quality improvement
What it is
Valerian (Valeriana officinalis) is a flowering plant, but it's the root that contains the active medicinal compounds, including valerenic acids and various iridoids. It has a distinct, pungent 'old gym bag' smell that is completely normal and indicative of its potency.
Mechanistically, valerian is thought to inhibit the breakdown of GABA in the brain, leading to a mild sedative effect. Unlike pharmaceutical sleep aids, valerian is not usually 'knock-out' strong on the first night. Its effects tend to build over 2-4 weeks of consistent use, making it better suited for chronic sleep issues than occasional acute insomnia.
What the research says
Valerian is one of the most studied herbal sleep aids. Meta-Analysis Evidence. A large meta-analysis published in the American Journal of Medicine concluded that valerian may improve sleep quality without producing significant side effects. Subjective Improvement. Participants consistently report falling asleep faster and having fewer nighttime awakenings. The 'Build-Up' Effect. Clinical trials, such as the one by Leathwood et al., suggest that the most significant benefits occur after 14 to 28 days of nightly use. It is less effective for 'one-off' use compared to melatonin or diphenhydramine. [1][2][3]
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Valerian on Amazon
Safety
Generally considered safe for up to 6 weeks in clinical trials. Some users experience 'vivid dreams' or a 'heavy' feeling the next morning. It should not be combined with alcohol or other heavy sedatives.
Interactions
- Benzodiazepines: May potentiate effects (e.g., Xanax, Valium).
- Alcohol: Increases sedation to potentially unsafe levels.
- CNS Depressants: General additive effect with surgical anesthesia; stop use 2 weeks before surgery.
Dosing
For Sleep: 450-600 mg of a standardized extract (0.8% valerenic acid) taken 30-60 minutes before bed. Form: Look for standardized root extract capsules to ensure potency and minimize the smell.
Cost
Inexpensive. Monthly costs range from $5 to $12 depending on the brand and dosage.
The bottom line
Valerian is a solid, evidence-backed choice for those looking for a 'natural' alternative to sleep drugs, provided you are willing to give it a few weeks to reach its full effect.
References
- Leach MJ, Page AT. Herbal medicine for insomnia: a systematic review and meta-analysis. Sleep Med Rev. 2015;24:1-12.
- Stevinson C, Ernst E. Valerian for insomnia: a systematic review of randomized clinical trials. Sleep Med. 2000;1(2):91-99.
- Valerian. National Institutes of Health Office of Dietary Supplements.
Sources for this page include published meta-analyses, systematic reviews, and NIH dietary supplement fact sheets. All claims reflect the evidence as of early 2026.
This is not medical advice. Consult your healthcare provider before starting any supplement, especially if you take medications.