All supplements/Artichoke extract

Artichoke extract

Cynara scolymus Extract
Also known as: Artichoke leaf extract, Cynarin
LiverMetabolic syndrome

TL;DR

  • Traditional Mediterranean remedy for liver and digestive health. Contains cynarin and chlorogenic acid. Evidence for cholesterol reduction and liver enzyme improvement.

  • Safety: Excellent. Very well-tolerated. Rare allergic reactions in people sensitive to Asteraceae family.

  • Cost: approximately $10-18/month.

  • Best for: Liver disease, Metabolic syndrome

What the research says

Evidence
3/5
Onset speed
2/5
Typical dose: 600-1200 mg/day

Several RCTs show improved liver enzymes and bile flow. Traditional choleretic use is supported by modern evidence. Modest but consistent benefits.

Evidence
3/5
Onset speed
3/5
Typical dose: 600-1200 mg/day

Meta-analyses show modest LDL and total cholesterol reduction. May also reduce blood glucose slightly.

Artichoke extract on Amazon

$10-18/mo (estimated)
See on Amazon

*Link is just for your convenience - we do not make any fees

Safety & practical info

Safety:Excellent

Very well-tolerated. Rare allergic reactions in people sensitive to Asteraceae family.

Interactions:Bile duct obstruction

Stimulates bile flow — contraindicated in bile duct obstruction. Otherwise minimal interactions.

Cost:$10-18/mo

Affordable standardized extract.

Sources for this page include published meta-analyses, systematic reviews, and NIH dietary supplement fact sheets. All claims reflect the evidence as of early 2026.

This is not medical advice. Consult your healthcare provider before starting any supplement, especially if you take medications.