Taurine

2-aminoethanesulfonic acid
Also known as: 2-aminoethanesulfonic acid
Amino Acid

Content by: OpenSupplement Editorial Team  |  Medical review: pending  |  Last updated: April 13, 2026

Supplement Score
Taurine1-2 g before bed | $5-10/mo
Safety5
Interactions4
Cost5
Evid.Onset
Heart disease
43
Metabolic syndrome
32
Sleep
34
Tinnitus
12
3 PubMed references cited
4–5 Strong2–3 Emerging1 Weak|Methodology

TL;DR

  • Amino acid-like molecule with massive benefits for heart and longevity

  • High evidence for lowering blood pressure and protecting the eyes

  • Moderate evidence for improving exercise performance and metabolic health

  • Acts as a 'calming' agent in the brain and a stabilizer in the heart

  • Extremely safe and very cheap

  • Cost: ~$5-10/month

  • Best for: Heart health, longevity, anxiety

What it is

Taurine is found in high concentrations in the heart, brain, and eyes. It is not a stimulant (despite being in energy drinks). It helps regulate minerals like calcium and magnesium in your cells. A landmark 2023 study in Science suggested that taurine deficiency is a driver of aging and that supplementation can increase lifespan in mammals.

What the research says

Relevance: High
Typical dose: 1-3 g/day

Taurine is the 'heart's favorite amino.' Evidence. Studies show that 3 grams of taurine daily can significantly lower blood pressure and improve the pumping function of the heart in people with congestive heart failure. It also reduces the 'stiffness' of the arteries. [1][2][3]

Relevance: Moderate
Typical dose: 1-3 g/day

Some trials show benefit for blood glucose and lipids. Anti-inflammatory effects may help metabolic markers.

Relevance: Moderate
Typical dose: 1-2 g before bed

GABA-ergic calming effects. Some evidence for sleep quality. Primarily studied for cardiovascular outcomes; sleep benefits secondary.

Relevance: Low
Typical dose: 1-2 g/day

Theoretical rationale via GABA-ergic inhibitory neuromodulation in the auditory system. No published RCTs for tinnitus specifically. Indirect benefits possible through calming effects and sleep improvement.

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Taurine on Amazon

$5-10/mo (estimated)
See on Amazon

Safety

Excellently safe. It is one of the most abundant molecules in the body. No known toxicity even at high doses.

Interactions

  • Lithium: May reduce the excretion of lithium.

Dosing

Standard Dose: 1-3 grams daily. Form: Powder is the cheapest and almost tasteless.

Cost

Dirt cheap. $5-10 per month.

The bottom line

Taurine is perhaps the best 'all-around' longevity supplement you've never heard of. It's safe, cheap, and supports your heart, eyes, and metabolism.

References

  1. MechanisticHeart diseasePubMed
  2. RCTHeart diseasePubMed
  3. ReviewHeart diseaseMetabolic syndromePubMed

Sources for this page include published meta-analyses, systematic reviews, and NIH dietary supplement fact sheets. All claims reflect the evidence as of early 2026.

This is not medical advice. Consult your healthcare provider before starting any supplement, especially if you take medications.